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Questions regarding the side effects of taking a Z-Pak should be discussed with one's pharmacist and medical provider. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment. ZITHROMAX is a macrolide antibiotic prescription medicine used in adults 18 years or older to treat certain infections caused by certain germs called bacteria. These bacterial infections include: acute worsening of chronic bronchitis acute sinus infection community-acquired pneumonia infected throat or tonsils skin infections infections of the urethra or cervix genital ulcers in men ZITHROMAX is also used in children to treat: ear infections community-acquired pneumonia infected throat or tonsils Azithromycin should not be taken by people who cannot tolerate oral medications because they are very ill or have certain other risk factors including: have cystic fibrosis have hospital acquired infections have known or suspected bacteria in the blood need to be in the hospital are elderly have any medical problems that can lower the ability of the immune system to fight infections ZITHROMAX is not for viral infections such as the common cold.

Before you take ZITHROMAX, tell your healthcare provider if you: have pneumonia have cystic fibrosis have known or suspected bacteremia bacterial infection in the blood have liver or kidney problems have an irregular heartbeat, especially a problem called "QT prolongation" have a problem that causes muscle weakness myasthenia gravis have any other medical problems are pregnant or plan to become pregnant.

Tell your healthcare provider about all the medicines you take , including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take: nelfinavir a blood thinner warfarin digoxin phenytoin an antacid that contains aluminum or magnesium Know the medicines you take.

Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Stop taking ZITHROMAX and get emergency medical help right away if you have any of the following symptoms of a severe allergic reaction: trouble breathing or swallowing swelling of the lips, tongue, face throat tightness, hoarseness rapid heartbeat faintness skin rash hives new onset of fever and swollen lymph nodes Stop taking ZITHROMAX at the first sign of a skin rash and call your healthcare provider.

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Liver damage hepatotoxicity. Call your healthcare provider right away if you have unexplained symptoms such as: nausea or vomiting loss of appetite stomach pain change in the color of your bowel movements fever weakness dark colored urine abdominal pain or tenderness yellowing of your skin or of the whites of your eyes itching unusual tiredness Stop taking ZITHROMAX and tell your healthcare provider right away if you have yellowing of your skin or white part of your eyes, or if you have dark urine. Serious heart rhythm changes QT prolongation and torsades de pointes.

Tell your healthcare provider right away if you have a change in your heartbeat a fast or irregular heartbeat , or if you feel faint and dizzy. This condition can cause an abnormal heartbeat and can be very dangerous. The chances of this happening are higher in people: who are elderly with a family history of prolonged QT interval with low blood potassium who take certain medicines to control heart rhythm antiarrhythmics Worsening of myasthenia gravis a problem that causes muscle weakness.

Call your healthcare provider right away if you have any worsening muscle weakness or breathing problems. Tell your healthcare provider right away if you have watery diarrhea, diarrhea that does not go away, or bloody stools. You may experience cramping and a fever.


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For the best experience on our site, be sure to turn on Javascript in your browser. Azithromycin belongs to the family of medications known as macrolide antibiotics. It is used to treat certain types of infections that are caused by bacteria. It is most commonly used to treat ear infections e. It can also be used to prevent mycobacterium avium complex MAC infections in people with HIV infection and to treat flare-ups of chronic obstructive pulmonary disease COPD caused by bacteria.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles.

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If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. When treating flare-ups of COPD, azithromycin can also be taken as two mg tablets once daily for 3 days.

Genitourinary tract infections can be treated with a single dose of mg 4 tablets of mg or mg 8 tablets of mg , depending on the type of bacteria causing the infection and the type of infection. The children's dose of azithromycin liquid suspension is based on body weight. When used to treat otitis media middle ear infection in children, a course of treatment of either 1 day, 3 days, or 5 days may be used.

The daily dose will vary depending on the number of treatment days. Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Azithromycin may also be given by injection to treat severe pneumonia or pelvic inflammatory disease. It is usually given in a hospital setting by a health professional. Your doctor will determine the appropriate dose of this medication.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor. Azithromycin must be taken for the recommended duration of treatment, even if you are feeling better. This will reduce the chances of having remaining bacteria grow back.

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The medication may be taken with or without food. Taking the medication with food may help to avoid stomach upset. It is important to take this medication exactly as prescribed by your doctor. Finish all of this medication, even if you start to feel better. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store all forms of this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Discard any unused suspension liquid after 10 days. Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


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  • Nonmedicinal ingredients: anhydrous citric acid and sodium hydroxide for pH adjustment. Nonmedicinal ingredients: anhydrous calcium phosphate dibasic, hypromellose, lactose, magnesium stearate, pregelatinized starch, sodium croscarmellose, sodium lauryl sulfate, titanium dioxide, and triacetin. Many medications can cause side effects.

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    A side effect is an unwanted response to a medication when it is taken in normal doses. These topical anti-infectives are not recommended in infants and children less than 1 year of age. Systemic use in children is associated with drug class side effects. Azithromycin is a macrolide-class anti-infective in the azalide subclass. It is synthesized from erythromycin and possesses a well-known safety and tolerability profile in both oral and intravenous forms. DuraSite has been used safely in ophthalmic applications before, but this is the full report of safety data from a phase 3 trial in which the system was used.

    Parts of these data have been reported in abstract form Protzko E et al. This research was conducted according to the tenets of the Declaration of Helsinki. Study investigators were approved by the governing institutional review boards for each site. Informed consent or parental assent was obtained from the participants after explanation of the nature and possible consequences of the study.

    The phase 3 trial was a prospective, randomized, active-controlled, double-masked study that was conducted at 47 sites from August 6, , to October 6, The primary assessment of safety and tolerability was based on measurements of adverse events, visual acuity, indirect ophthalmoscopy, and biomicroscopy. The extent of recurrence of the original pathogen and presence of novel bacteria at different time points in the study were also used as a measure of safety.

    The study design is shown in Figure 1. Participants were randomized and instructed to instill masked medication four times daily at 4—6 hour intervals on days 1 through 5. To mask this study, subjects were given four bottles for each day. For masking, the intermediate doses contained the formulation vehicle. A total of participants were enrolled.

    The records for four participants were lost in centers that were damaged during Hurricane Katrina in Of the remaining participants, The two treatment groups had similar overall discontinuation rates. Thirty-three participants were terminated from the study before completion Table 1.